Toxicology tests or safety assessment tests are generally conducted to test the levels of toxicity present in a substance that could effectively damage living and non living organisms. These tests are primarily conducted on primate and non primates before the usage of that drug is made officially usable for human beings. Countries of the European Union have banned the experiments conducted on animals for cosmetic purposes. Toxicity tests are crucial parts of pre clinical testing procedures. They are carried out in various fields of pharmacology, biotechnology and are done in various contact research organizations. A contact research organization (CRO) facilitates various assessment procedures and supports pharmaceutical, bio technological, medical and other forms of industries. Pesticides, medications, cosmetics, food additiveslike artificial sweeteners, packing materials, air fresheners and any specific chemical ingredient present in these materials can be made to undergo toxicology procedures. It can be carried out through various methodologies which generally entail the consumption of drugs through food intake by animals. Tests are also carried out through injecting drugs or by applying them on the skin or eyes.
Market value of early toxicity testing:
The global market value of early toxicity testing sector has increased manifold in the recent years due to its wide scope of applications in various fields. Some of the fields include pharmaceutical industries, diagnostics sector, foods and beverages industry, chemical producing industries, cosmetics manufactory and other industries. The market revenue yield is concentrated on the leading producing countries like United States, Japan, China, India and countries of European Union. The market also focuses on the types of assessment methodologies available in the early toxicity testing sector which includescell-based ELISA and western blots, enzyme toxicity assays, tissues culture assays,bacterial toxicity assays, and receptor binding assays. Market analysts have stated that the Cumulative Average Growth Rate (CAGR) percent is said to increase by a considerable amount in the impending years. There are generally three techniques followed. They are in vivo (encompasses usage of living animals), in vitro (involves various bio chemical and cellular assessment procedures) and in silico (involves data analysis with the aid of computers).
The Organizations supportive of animal and environmental protection pressurize government to suppress the in vivo approach and ask them to take up the in silico approach. However, new technological advancements have happened in the in vivo procedure. Reportedly, majority of drugs are eliminated due to late toxicity test reports. This consequently affects the market growth rate of pharmaceutical, medical and various other industries. Hence, early toxicity tests have become indispensable.
The switch over to harm free test methodologies and new advancements which supposedly entails the usage of nano particles could drive this market.